Article

A General Biphasic-Bodyweight Model for Scaling Basal Metabolic Rate, Glomerular Filtration Rate and Drug Clearance from Birth to Adulthood

2021-07-26

Abstract excerpt

Understanding the maturation process of human physiology and metabolism has broad medical and pharmaceutical implications. Age and bodyweight are frequently considered as separate variables in modeling the dynamical changes of human organ functions and of drug clearance from birth to adulthood. The objective of this study is to propose a unified, continuous and bodyweight-only equation to quantify the changes of h...

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Literature Corpus work: c16badb7-7bcb-51e6-83ca-0efb53f45aa6
DOI: 10.1101/2021.07.25.453668

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