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Ontogeny of Hepatic Glucuronidation; Methods and Results

1 Jun 2012

Abstract excerpt

The onset and maturation, or so-called ontogeny, of hepatic glucuronidation is important for the clearance of a number of drugs in children. The current review discusses methods for studying the ontogeny of liver enzyme systems and specifically focuses on the results obtained with these methods for uridine 5'-diphosphate glucuronosyltransferases (UGTs). The number of contributing components in the biological...

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PMID: 22452455
DOI: 10.2174/138920012800840455

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