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A Physiologically Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children

2020-12-17

Abstract excerpt

Malnutrition in children is a global health problem, particularly in developing countries. The effects of an insufficient supply of nutrients on body composition and physiological functions may have implications for drug disposition and ultimately affect the clinical outcome in this vulnerable population. Physiologically based pharmacokinetic (PBPK) modeling can be used to predict the effect of malnutrition as it...

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Literature Corpus work
1c701500-1a18-5479-afdd-c0bdc2069599
DOI
10.20944/preprints202012.0437.v1
Open publication

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A Physiologically Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished ChildrenDOI 10.20944/preprints202012.0437.v1
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