Article

MDM2-linked microglial dysfunction in obsessive-compulsive disorder

2026-04-17

Abstract excerpt

<title>Abstract</title> <p>Microglia, the resident immune cells of the central nervous system, are essential for immune surveillance and synaptic remodeling, and have been implicated in various neuropsychiatric disorders. However, their role in the pathophysiology of obsessive-compulsive disorder (OCD) remains unclear. Here we identify molecular and functional impairments in induced microglia-like cells (iMGs) de...

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Literature Corpus work: c16b5e25-ef28-55fc-9e7e-442e5802308a
DOI: 10.21203/rs.3.rs-9325069/v1

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