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Article

Oncostatin M protects against demyelination by inducing a protective microglial phenotype.

Glia - 1 Oct 2015

Janssens Kris, Maheshwari Anurag, Van den Haute Chris, Baekelandt Veerle, Stinissen Piet, Hendriks Jerome J A, Slaets Helena, Hellings Niels

Abstract excerpt

Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system (CNS), in which destruction of myelin sheaths leads to disturbed axonal conduction. Available MS therapies modulate the immune response, but are unable to prevent neurological decline. Therefore, great efforts are made to develop therapies that limit demyelination and axonal degeneration. Oncostatin M (OSM), a member of the...

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Share to Calcium-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25921393
DOI: 10.1002/glia.22840

Genes

OSM
OSMR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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