Article

Identification and experimental validation of biomarkers related to mitochondrial and programmed cell death in obsessive-compulsive disorder

2025-07-23

Abstract excerpt

<title>Abstract</title> <p>Background Obsessive-compulsive disorder (OCD) poses a substantial global challenge in identifying biomarkers linked to mitochondrial-related genes (MRGs) and programmed cell death-related genes (PCD-RGs), offering new insights into the disorder's pathogenesis. Methods Differentially expressed genes (DEGs) between OCD and control samples were identified from the GSE78104 dataset. Differ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1067887a-e0a8-5bb2-b200-82bdd73399ff
DOI: 10.21203/rs.3.rs-6869315/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification and experimental validation of biomarkers related to mitochondrial and programmed cell death in obsessive-compulsive disorderDOI 10.21203/rs.3.rs-6869315/v1Read

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorderSemantic proximity Read

Proteomic Analysis Reveals sympathetic system and immune-inflammation biomarkers in serum of drug-free obsessive-compulsive disorderSemantic proximity Read

Rare coding variation in OCD implicates shared genes with other psychiatric disordersSemantic proximity Read

Genome-wide analyses indirectly implicate miRNA regulatory mechanisms in Obsessive-compulsive Disorder psychopathologySemantic proximity Read

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.Semantic proximity Read

Advancements in the Understanding of the Genetics of Obsessive-Compulsive Disorder (OCD).Semantic proximity Read

Genome-wide association study identifies new loci associated with OCDSemantic proximity Read

MDM2-linked microglial dysfunction in obsessive-compulsive disorderSemantic proximity Read

Genome-wide association study of obsessive-compulsive disorder.Semantic proximity Read

Alterations of cellular aging markers in obsessive–compulsive disorder: mitochondrial DNA copy number and telomere lengthSemantic proximity Read

Transcriptomes of higher order thalamic nuclei in obsessive compulsive disorderSemantic proximity Read

Obsessive-compulsive disorder, which genes? Which functions? Which pathways? An integrated holistic view regarding OCD and its complex genetic etiology.Semantic proximity Read