Article

IRF8 deficiency causes anxiety-like behavior in a sex-dependent manner

2025-09-04

Abstract excerpt

Anxiety disorder is a serious psychiatric disease that affects women twice more than men and disrupts patients’ daily lives. It is often comorbid with major depression and other mental diseases. Various underlying mechanisms have been proposed, such as neurotransmitters and neuroanatomical disruptions, and more recently, oxidative stress; however, much remained unclear, including the role of glial cells. Here, we...

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Literature Corpus work: ba225e38-d687-5532-a309-439824340419
DOI: 10.1101/2025.09.02.673764

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