Article

Ultrastructural Changes in the Striatum of the Slitrk5-/- Mouse Model of Obsessive-Compulsive Disorder using Volume Electron Microscopy

2024-10-11

Abstract excerpt

Studies in obsessive-compulsive disorder (OCD) have suggested rare, damaging coding variants in the SLIT and NTRK-like family member 5 (Slitrk5) gene as possible contributors to the disorder. Here we identify previously unrecognized pathological changes in the dorsomedial striatum of a Slitrk5 knockout mouse model using serial block-face scanning electron microscopy. Following a combination of manual annotation an...

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Literature Corpus work: 029fb976-015e-554e-8466-5acbe6e1439b
DOI: 10.22541/au.172868270.06295613/v1

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Ultrastructural Changes in the Striatum of the Slitrk5-/- Mouse Model of Obsessive-Compulsive Disorder using Volume Electron MicroscopyDOI 10.22541/au.172868270.06295613/v1Read

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