The Autolysin LytA Contributes to Efficient Bacteriophage Progeny Release in <i>Streptococcus pneumoniae</i>

Abstract excerpt

Most bacteriophages (phages) release their progeny through the action of holins that form lesions in the cytoplasmic membrane and lysins that degrade the bacterial peptidoglycan. Although the function of each protein is well established in phages infecting Streptococcus pneumoniae, the role--if any--of the powerful bacterial autolysin LytA in virion release is currently unknown. In this study, deletions of the...

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