Article
Genetic analysis of the T4 holin: timing and topology.
Gene - 7 Mar 2001
Ramanculov E, Young R
Abstract excerpt
The t protein of bacteriophage T4 shares with other holins the ability to cause the formation of a lethal membrane lesion which allows the phage endolysin to attack the peptidoglycan. Moreover, T, like other holins, acts in a saltatory manner at a precisely programmed time in the vegetative cycle. Unlike other holins, however, T has the unique ability to postpone its lethal function in response to a secondary...
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