Article
Rapid de novo evolution of lysis genes in single-stranded RNA phages.
Nature communications - 26 Nov 2020
Chamakura Karthik R, Tran Jennifer S, O'Leary Chandler, Lisciandro Hannah G, Antillon Sophia F, Garza Kameron D, Tran Elizabeth, Min Lorna, Young Ry
Abstract excerpt
Leviviruses are bacteriophages with small single-stranded RNA genomes consisting of 3-4 genes, one of which (sgl) encodes a protein that induces the host to undergo autolysis and liberate progeny virions. Recent meta-transcriptomic studies have uncovered thousands of leviviral genomes, but most of these lack an annotated sgl, mainly due to the small size, lack of sequence similarity, and embedded nature of these...
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