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Article

The Last r Locus Unveiled: T4 RIII Is a Cytoplasmic Antiholin.

Journal of bacteriology - 15 Sept 2016

Chen Yi, Young Ry

Abstract excerpt

UNLABELLED: The latent period of phage T4, normally ∼25 min, can be extended indefinitely if the infected cell is superinfected after 5 min. This phenomenon, designated lysis inhibition (LIN), was first described in the 1940s and is genetically defined by mutations in diverse T4 r genes. RI, the main effector of LIN, has been shown to be secreted to the periplasm, where, upon activation by superinfection with a...

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PMID: 27381920
DOI: 10.1128/JB.00294-16
PMCID: PMC4999926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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