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Article

Phage lytic proteins: biotechnological applications beyond clinical antimicrobials

21 Jan 2015

Abstract excerpt

Most bacteriophages encode two types of cell wall lytic proteins: endolysins (lysins) and virion-associated peptidoglycan hydrolases. Both enzymes have the ability to degrade the peptidoglycan of Gram-positive bacteria resulting in cell lysis when they are applied externally. Bacteriophage lytic proteins have a demonstrated potential in treating animal models of infectious diseases. There has also been an...

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PMID: 25603721
DOI: 10.3109/07388551.2014.993587

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