Article

Biological networks and GWAS: comparing and combining network methods to understand the genetics of familial breast cancer susceptibility in the GENESIS study

2020-05-05

Abstract excerpt

Network approaches to disease use biological networks, which model functional relationships between the molecules in a cell, to generate hypotheses about the genetics of complex diseases. Several among them jointly consider gene scores, representing the association between each gene and the disease, and the biological context of each gene, modeled by a network. Here, we study six such network methods using gene sc...

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Literature Corpus work: c133efb3-292b-5fc4-bf26-1e1cf27ac028
DOI: 10.1101/2020.05.04.076661

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