Article
Hope for GWAS: relevant risk genes uncovered from GWAS statistical noise.
International journal of molecular sciences - 29 Sept 2014
Correia Catarina, Diekmann Yoan, Vicente Astrid M, Pereira-Leal José B
Abstract excerpt
Hundreds of genetic variants have been associated to common diseases through genome-wide association studies (GWAS), yet there are limits to current approaches in detecting true small effect risk variants against a background of false positive findings. Here we addressed the missing heritability problem, aiming to test whether there are indeed risk variants within GWAS statistical noise and to develop a...
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