Article

Analysis of tumor-derived and cross-presented peptide antigens defines improved immunotherapeutic strategies

2026-02-25

Abstract excerpt

<h4>Background</h4> Cross-presentation of tumor antigens by antigen-presenting cells (APCs) is essential for initiating effective anti-tumor T cell immunity. The presence of cross-presenting immune cells across multiple solid tumors correlates with improved clinical outcomes. Despite the importance of this process, the identities and characteristics of tumor-derived MHC-I antigens that are cross-presented by APCs...

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Literature Corpus work: c116860d-c069-51b7-a974-b5689d8f9162
DOI: 10.64898/2026.02.23.707477

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