Article

Cholesterol esterification blockade boosts immunotherapy and reduces cancer relapse

2025-10-16

Abstract excerpt

Recurrence after liver cancer resection and transplantation remains a critical clinical challenge, driven by immune evasion. However, effective immune-sensitizing targets for preventing or managing relapse remain limited. In this study, we integrated differential proteomic profiling of human liver cancer samples with or without subsequent recurrence and T cell killing assays to uncover a pivotal role for the chole...

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Literature Corpus work: c1151e15-97ed-54aa-8d5b-6ea97cdd4182
DOI: 10.1101/2025.10.15.682531

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