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Article

Single-cell and spatial atlas of steatotic liver disease-related hepatocellular carcinoma

2024-05-14

Abstract excerpt

<h4>Summary</h4> Steatotic liver disease-related hepatocellular carcinoma (SLD-HCC) poses significant challenges in liver cancer management. Our current study investigates the tumor microenvironment (TME) of SLD-HCC using single-cell transcriptomic, proteomic and spatial transcriptomic analyses. We identified altered immune-related and lipid metabolism pathways, particularly in regulatory T cells (Tregs) and canc...

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Literature Corpus work
26267fa7-7259-50da-aa78-61760ba33f54
DOI
10.1101/2024.05.09.593073
Open publication

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Single-cell and spatial atlas of steatotic liver disease-related hepatocellular carcinomaDOI 10.1101/2024.05.09.593073
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