Article

Genetically-Modified Macrophages Accelerate Myelin Repair

2020-10-28

Abstract excerpt

<h4>ABSTRACT</h4> Preventing neurodegeneration-associated disability progression in patients with multiple sclerosis (MS) remains an unmet therapeutic need. As remyelination prevents degeneration of demyelinated axons, promoting this process in patients might halt the development of permanent disability. In demyelinating mouse lesions, local overexpression of Semaphorin 3F (Sema3F), an oligodendrocyte progenitor...

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Literature Corpus work: c0ff5efb-0c2f-59c5-b1cf-2b6d8f3bccf5
DOI: 10.1101/2020.10.28.358705

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