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The reset of aging counters in the germline and early embryo: a systematic review of centriole, telomere, mitochondrial, and epigenetic clocks across seven developmental transitions

2026-08-24

Abstract excerpt

<title>Abstract</title> <p>Cellular aging is commonly framed as the accumulation of molecular damage, yet a single mitotic lineage carries an age structure across generations while each new germline and embryonic cycle appears to reset it. We performed a systematic review (PubMed, Semantic Scholar, Crossref; from inception through 21 August 2026) of quantitative evidence on four aging counters (the centriole, the...

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Literature Corpus work
c0e8b1ef-9e46-5f8d-92f2-e7deb091f7a8
DOI
10.21203/rs.3.rs-10776270/v1
Open publication

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The reset of aging counters in the germline and early embryo: a systematic review of centriole, telomere, mitochondrial, and epigenetic clocks across seven developmental transitionsDOI 10.21203/rs.3.rs-10776270/v1
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