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Article

Counting divisions in a human somatic cell tree: how, what and why?

Cell cycle (Georgetown, Tex.) - 1 Mar 2006

Shibata Darryl, Tavaré Simon

Abstract excerpt

The billions of cells within an individual can be organized by genealogy into a single somatic cell tree that starts from the zygote and ends with present day cells. In theory, this tree can be reconstructed from replication errors that surreptitiously record divisions and ancestry. Such a molecular clock approach is currently impractical because somatic mutations are rare, but more feasible measurements are...

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Identifiers

PMID: 16582617
DOI: 10.4161/cc.5.6.2570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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