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A germ cell‐specific ageing pattern in otherwise healthy men

20 Sept 2020

Abstract excerpt

Life-long sperm production leads to the assumption that male fecundity remains unchanged throughout life. However, recently it was shown that paternal age has profound consequences for male fertility and offspring health. Paternal age effects are caused by an accumulation of germ cell mutations over time, causing severe congenital diseases. Apart from these well-described cases, molecular patterns of ageing in...

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PMID: 32951333
DOI: 10.1111/acel.13242

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