Article

A novel dual antibody staining assay to measure estrogen receptor transcriptional activity

2020-04-14

Abstract excerpt

Activity of the canonical estrogen receptor (ER) pathway is equivalent to functional activity of the nuclear ER transcription factor. To assess transcriptional activity of ER, for biomedical research and diagnostic purposes ER monoclonal antibodies are routinely used to identify nuclear ER staining in cells and tissue samples, however it remained unclear whether this is sufficiently predictive for transcriptional...

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Literature Corpus work: c0d357aa-39dd-585c-8c2d-7ab44dddeb43
DOI: 10.1101/2020.04.14.021782

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