Article
Gene transcription regulation by ER at the single cell and allele level.
Steroids - 1 Dec 2023
Stossi Fabio, Rivera Tostado Alejandra, Johnson Hannah L, Mistry Ragini M, Mancini Maureen G, Mancini Michael A
Abstract excerpt
In this short review we discuss the current view of how the estrogen receptor (ER), a pivotal member of the nuclear receptor superfamily of transcription factors, regulates gene transcription at the single cell and allele level, focusing on in vitro cell line models. We discuss central topics and new trends in molecular biology including phenotypic heterogeneity, single cell sequencing, nuclear phase separated...
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