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AR/ER Ratio Correlates with Expression of Proliferation Markers and with Distinct Subset of Breast Tumors

24 Apr 2020

Abstract excerpt

The co-expression of androgen (AR) and estrogen (ER) receptors, in terms of higher AR/ER ratio, has been recently associated with poor outcome in ER-positive (ER+) breast cancer (BC) patients. The aim of this study was to analyze if the biological aggressiveness, underlined in ER+ BC tumors with higher AR/ER ratio, could be due to higher expression of genes related to cell proliferation. On a cohort of 47 ER+ BC...

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PMID: 32344660
DOI: 10.3390/cells9041064

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