Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The E-Morph Screening Assay: Phenotypic Screening for Estrogenic or Anti-estrogenic Compound Activities.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Aßmann Ann-Sophie, Dunst Sebastian, Fetz Verena

Abstract excerpt

The unintended exposure to compounds interfering with the estrogen hormone system can pose a threat to human health and the environment. In this chapter, we describe the E-Morph Screening Assay, a targeted imaging-based high-throughput phenotypic screening assay that allows the efficient identification and characterization of such compounds with estrogenic or anti-estrogenic activities in a 96- or 384-well plate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adherens Junctions
Share to Breast Neoplasms
Share to Cadherins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Evaluation, Preclinical

Share to Estrogen Antagonists

Share to Estrogens

Share to High-Throughput Screening Assays

Share to MCF-7 Cells

Source

Identifiers

PMID: 41479049
DOI: 10.1007/978-1-0716-4985-5_5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The E-Morph Screening Assay: Phenotypic Screening for Estrogenic or Anti-estrogenic Compound Activities.PMID 41479049Read ↗

Estrogen Receptors: How Do They Signal and What Are Their TargetsSemantic proximity Read ↗

High-resolution phenotypic profiling of natural products-induced effects on the single-cell level.Semantic proximity Read ↗

Applying Cell Painting in Non-Tumorigenic Breast Cells to Understand Impacts of Common Chemical ExposuresSemantic proximity Read ↗

Gene transcription regulation by ER at the single cell and allele level.Semantic proximity Read ↗

Evaluating steroid hormone receptor interactions using the live-cell NanoBRET proximity assaySemantic proximity Read ↗

Integrated Model of Chemical Perturbations of a Biological Pathway Using 18In VitroHigh-Throughput Screening Assays for the Estrogen ReceptorSemantic proximity Read ↗

Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.Semantic proximity Read ↗

Image-based phenotypic profiling of a chemogenomic screening library identifies novel druggable targets in the EGFR-pathwaySemantic proximity Read ↗

A highly efficient and sensitive screening method for trans-activation activity of estrogen receptors.Semantic proximity Read ↗

A molecular toolbox to study progesterone receptor signalingSemantic proximity Read ↗

Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds.Semantic proximity Read ↗

Stereo-specific Lasofoxifene Derivatives Reveal the Interplay between Estrogen Receptor Alpha Stability and Antagonistic Activity in ESR1 Mutant Breast Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.