Article

iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease

2024-02-13

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disorder caused by complex genetic and environmental factors. Genome-edited human pluripotent stem cells (hPSCs) offer a unique experimental platform to advance our understanding of PD etiology by enabling the generation of disease-relevant cell types carrying patient mutations along with isogenic control cells. To facilitate this approach, we generated a collection...

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Literature Corpus work: c0bd85e7-750e-5161-9b32-1d43e981f185
DOI: 10.1101/2024.02.12.579917

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