Article

The class XIV myosin of <i>Toxoplasma gondii</i> , TgMyoA, is druggable in an animal model of infection

2022-09-09

Abstract excerpt

Toxoplasma gondii is a widespread apicomplexan parasite that can cause severe disease in its human hosts. The ability of T. gondii and other apicomplexan parasites to invade into, egress from, and move between cells of the hosts they infect is critical to parasite virulence and disease progression. An unusual and highly conserved parasite myosin motor (TgMyoA) plays a central role in T. gondii motility. The goal...

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Literature Corpus work: c0a98664-190d-5103-9670-1caf873c28a4
DOI: 10.1101/2022.09.09.507210

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