Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A small-molecule approach to studying invasive mechanisms of <i>Toxoplasma gondii</i>

3 May 2004

Abstract excerpt

Toxoplasma gondii is the most common protozoan parasite of humans. Infection with T. gondii can lead to life-threatening disease as a result of repeated cycles of host cell invasion, parasite replication, and host cell lysis. Relatively little is known about the invasive mechanisms of T. gondii and related parasites within the Phylum Apicomplexa (including Plasmodium spp., the causative agents of malaria), due to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15123807
DOI: 10.1073/pnas.0307769101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A small-molecule approach to studying invasive mechanisms of <i>Toxoplasma gondii</i>PMID 15123807Read ↗

Chemical genetic screen identifies <i>Toxoplasma</i> DJ-1 as a regulator of parasite secretion, attachment, and invasionSemantic proximity Read ↗

Cysteine Protease Inhibitors Block <i>Toxoplasma gondii</i> Microneme Secretion and Cell InvasionSemantic proximity Read ↗

A Focused Small-Molecule Screen Identifies 14 Compounds with Distinct Effects on Toxoplasma gondiiSemantic proximity Read ↗

Signaling Cascades Governing Entry into and Exit from Host Cells by Toxoplasma gondiiSemantic proximity Read ↗

The class XIV myosin of <i>Toxoplasma gondii</i> , TgMyoA, is druggable in an animal model of infectionSemantic proximity Read ↗

How does Toxoplama gondii invade host cells?Semantic proximity Read ↗

4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion.Semantic proximity Read ↗

A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by <i>Toxoplasma</i>Semantic proximity Read ↗

MyosinA is a druggable target in the widespread protozoan parasite Toxoplasma gondii.Semantic proximity Read ↗

The glideosome: a molecular machine powering motility and host-cell invasion by ApicomplexaSemantic proximity Read ↗

Microtubules as antiparasitic drug targetsSemantic proximity Read ↗

Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.