Article
Myosin-dependent cell-cell communication controls synchronicity of division in acute and chronic stages of Toxoplasma gondii.
Nature communications - 8 Jun 2017
Frénal Karine, Jacot Damien, Hammoudi Pierre-Mehdi, Graindorge Arnault, Maco Bohumil, Soldati-Favre Dominique
Abstract excerpt
The obligate intracellular parasite Toxoplasma gondii possesses a repertoire of 11 myosins. Three class XIV motors participate in motility, invasion and egress, whereas the class XXII myosin F is implicated in organelle positioning and inheritance of the apicoplast. Here we provide evidence that TgUNC acts as a chaperone dedicated to the folding, assembly and function of all Toxoplasma myosins. The conditional...
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