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Article

Chemical genetic screen identifies <i>Toxoplasma</i> DJ-1 as a regulator of parasite secretion, attachment, and invasion

13 Jun 2011

Abstract excerpt

Toxoplasma gondii is a member of the phylum Apicomplexa that includes several important human pathogens, such as Cryptosporidium and Plasmodium falciparum, the causative agent of human malaria. It is an obligate intracellular parasite that can cause severe disease in congenitally infected neonates and immunocompromised individuals. Despite the importance of attachment and invasion to the success of the parasite,...

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PMID: 21670272
DOI: 10.1073/pnas.1105622108

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