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Retinal Transcriptome-Wide Association Study Identifies Novel Alzheimer’s Disease Risk Genes

2026-07-04

Abstract excerpt

<h4>INTRODUCTION</h4> Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The retina shares molecular pathways with the brain, yet no study has systematically linked retinal gene expression to AD risk. <h4>METHODS</h4> We performed transcriptome-wide association studies (TWAS) using two independent retinal eQTL panels (Strunz et al., n = 311; EyeGEx, n = 406) and a large meta-analyzed AD genome-...

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Literature Corpus work
c09c122b-3646-570e-9e99-476fe7102de4
DOI
10.64898/2026.07.01.26357036
Open publication

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Retinal Transcriptome-Wide Association Study Identifies Novel Alzheimer’s Disease Risk GenesDOI 10.64898/2026.07.01.26357036
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