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Article

Multilevel genomic, transcriptomic, and epidemiologic evidence linking diabetic retinopathy to Alzheimer disease.

Journal of global health - 4 Sept 2026

Li Jing, Liu Qian, Ma Qian, Shen Ting, Xia Jiao, Yang Xiongyi, Liu Kun, Li Na, Yan Biao

Abstract excerpt

Background: Diabetic retinopathy (DR) and Alzheimer disease (AD) share metabolic and vascular dysfunctions, but the extent to which they reflect overlapping genetic susceptibility and neurovascular-metabolic regulatory pathways remains unclear. We combined multi-omics analyses with population-based data to examine the genetic convergence, cellular pathways, and longitudinal association between DR and AD. Methods:...

Read the complete abstract on PubMed

Topics

Humans
Alzheimer Disease
Diabetic Retinopathy
Mendelian Randomization Analysis
Transcriptome
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genomics

Multiomics

Bayes Theorem

Source

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Identifiers

PMID: 42693903
DOI: 10.7189/jogh.16.04311
PMCID: PMC13542801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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