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Article

G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum.

Nucleic acids research - 2 Dec 2021

Dumetz Franck, Chow Eugene Yui-Ching, Harris Lynne M, Liew Shiau Wei, Jensen Anders, Umar Mubarak I, Chung Betty, Chan Ting Fung, Merrick Catherine J, Kwok Chun Kit

Abstract excerpt

G-quadruplexes are non-helical secondary structures that can fold in vivo in both DNA and RNA. In human cells, they can influence replication, transcription and telomere maintenance in DNA, or translation, transcript processing and stability of RNA. We have previously showed that G-quadruplexes are detectable in the DNA of the malaria parasite Plasmodium falciparum, despite a very highly A/T-biased genome with...

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Identifiers

PMID: 34792144
DOI: 10.1093/nar/gkab1095
PMCID: PMC8643661

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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