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Discovery of G-quadruplex-forming sequences in SARS-CoV-2

13 May 2020

Abstract excerpt

The outbreak caused by the novel coronavirus SARS-CoV-2 has been declared a global health emergency. G-quadruplex structures in genomes have long been considered essential for regulating a number of biological processes in a plethora of organisms. We have analyzed and identified 25 four contiguous GG runs (G2NxG2NyG2NzG2) in the SARS-CoV-2 RNA genome, suggesting putative G-quadruplex-forming sequences (PQSs)....

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PMID: 32484220
DOI: 10.1093/bib/bbaa114

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