Article

Identification of Aberrantly Methylated and Silenced Genes in Acute Myeloid Leukemia by Combined Methylation/expression Analysis

2020-10-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Aberrant genomic methylation plays an important role in pathogenic process of acute myeloid leukemia (AML) by silencing tumor suppressor genes (TSG). While the key aberrantly methylated genes and related pathways have not been well understood yet, which we aimed to reveal by combined analysis of methylation and expression datasets. The prognostic significance was...

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Literature Corpus work: c04f24a8-b2d9-5ab2-8a0d-da90e4fe7d14
DOI: 10.21203/rs.3.rs-87795/v1

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