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Identification of aberrantly methylated differentially expressed genes targeted by differentially expressed miRNA in osteosarcoma

1 Mar 2020

Abstract excerpt

BACKGROUND: Osteosarcoma (OS) is the most common primary bone tumors diagnosed in children and adolescents. Recent studies have shown a prognostic role of DNA methylation in various cancers, including OS. The aim of this study was to identify the aberrantly methylated genes that are prognostically relevant in OS. METHODS: The differentially expressed mRNAs, miRNAs and methylated genes (DEGs, DEMs and DMGs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32355817
DOI: 10.21037/atm.2020.02.74

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