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DNA methylation-based prognostic biomarkers of acute myeloid leukemia patients

1 Dec 2019

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous clonal disease that prevents normal myeloid differentiation with its common features. Its incidence increases with age and has a poor prognosis. Studies have shown that DNA methylation and abnormal gene expression are closely related to AML. METHODS: The methylation array data and mRNA array data are from the Gene Expression Omnibus (GEO) database....

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PMID: 32042753
DOI: 10.21037/atm.2019.11.122

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