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Article

Genetic architecture of gene expression traits across diverse populations.

PLoS genetics - 1 Aug 2018

Mogil Lauren S, Andaleon Angela, Badalamenti Alexa, Dickinson Scott P, Guo Xiuqing, Rotter Jerome I, Johnson W Craig, Im Hae Kyung, Liu Yongmei, Wheeler Heather E

Abstract excerpt

For many complex traits, gene regulation is likely to play a crucial mechanistic role. How the genetic architectures of complex traits vary between populations and subsequent effects on genetic prediction are not well understood, in part due to the historical paucity of GWAS in populations of non-European ancestry. We used data from the MESA (Multi-Ethnic Study of Atherosclerosis) cohort to characterize the...

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Identifiers

PMID: 30096133
DOI: 10.1371/journal.pgen.1007586
PMCID: PMC6105030

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CHURC1
TACSTD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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