Article

CpG Island Methylator Phenotype(CIMP) is An Independent Prognostic Marker with Tumor-Promoting Functions in Colorectal Cancer

2020-09-24

Abstract excerpt

<h4>Background: </h4> The CpG island methylator phenotype(CIMP)with extensive promoter methylation isa distinct epigenotype incolorectal cancer (CRC). Changes in microbiota and epigenetic dysregulation mightbe the key underlying mechanism.MethodsTissueswith stages I–III cancerwere collected afterproctocolectomy. The 16S rRNA gene sequencing was carried to determine the differences in microbiota.Subsequently,BRAF m...

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Literature Corpus work: c02ee71e-feef-542d-83e6-b595bad51a1c
DOI: 10.21203/rs.3.rs-76992/v1

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