Article

Acute opioid responses are modulated by dynamic interactions of <i>Oprm1</i> and <i>Fgf12</i>

2022-03-12

Abstract excerpt

Exploring the molecular genetic cascades responsible for behavioral responses to opioids can improve our understanding of drug use initiation. We generated high-precision time-series data for 105 morphine-and naloxone-related traits across ∼700 young adult BXD mice (64 diverse strains and both sexes) for 3 hours after a single morphine injection. Variations in responses were mapped using high-precision genome sequ...

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Literature Corpus work: bfefd84c-a3ee-5bcf-9266-1de45f973555
DOI: 10.1101/2022.03.11.483993

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