Article
Causal Inference of CLEC5A and ISG20 in Atherosclerosis: Integrating Mendelian Randomization and eQTL Evidence
2025-05-09
Abstract excerpt
<h4>Background: </h4> Atherosclerosis (AS) is a vascular disease driven by lipid deposition and chronic inflammation, with pathogenesis linked to genetic and immune dysregulation. This study aimed to systematically identify AS-associated genes, elucidate their molecular mechanisms, and explore therapeutic targets by integrating multi-omics analyses and experimental validation. <h4>Methods:</h4> AS-associated genes...
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Identifiers and source
- Literature Corpus work
- bfecd407-8b80-5762-a80c-70dc86ff07c2
- DOI
- 10.20944/preprints202505.0713.v1
