Article

Integrated bioinformatics and single-cell analysis identifies vascular aging-related hub genes and immune drivers in atherosclerosis

2026-04-17

Abstract excerpt

Atherosclerosis (AS) is a chronic inflammatory disease closely linked to vascular senescence, yet the specific molecular mechanisms connecting aging processes to AS pathogenesis remain incompletely understood. This study integrated transcriptomic data from GEO datasets (GSE100927 and GSE43292) to identify vascular aging-related differentially expressed genes (VARDEGs). Following batch effect correction, 28 VARDEGs...

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Literature Corpus work: 8fb15ac2-ba03-5e85-a776-99d95e91a37b
DOI: 10.64898/2026.04.14.718580

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