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Critical gene signature and immunological characterization in peripheral vascular atherosclerosis: novel insights from mendelian randomization and transcriptomics

10 Apr 2024

Abstract excerpt

Introduction: Peripheral vascular atherosclerosis (PVA) is a chronic inflammatory disease characterized by lipid accumulation in blood vessel walls, leading to vessel narrowing and inadequate blood supply. However, the molecular mechanisms underlying PVA remain poorly understood. In this study, we employed a combination of Mendelian randomization (MR) analysis and integrated transcriptomics to identify the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38660678
DOI: 10.3389/fgene.2024.1361445

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