Article
Association of Multigenerational Family History of Depression With Lifetime Depressive and Other Psychiatric Disorders in Children: Results from the Adolescent Brain Cognitive Development (ABCD) Study.
JAMA psychiatry - 1 Jul 2021
van Dijk Milenna T, Murphy Eleanor, Posner Jonathan E, Talati Ardesheer, Weissman Myrna M
Abstract excerpt
Importance: Three-generation family studies of depression have established added risk of psychopathology for offspring with 2 previous generations affected with depression compared with 1 or none. Because of their rigorous methodology, there are few of these studies, and existing studies are limited by sample sizes. Consequently, the 3-generation family risk paradigm established in family studies can be a...
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