Article

Advanced HCC precision modeling reveals divergent responses to combinatorial immunotherapy

2022-08-08

Abstract excerpt

<title>Abstract</title> <p>Combinatorial immunotherapy (CIT) has afforded patients with advanced HCC a potential for long-term survival. However, sustained responses are seen only in a minority of patients. Thus, there is an unmet need for precision modeling to differentiate responder vs. non-responders and uncover predictive biomarkers. Here, we establish mouse models to mimic genetic alterations of human HCC by...

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Literature Corpus work: bfaec056-3e41-5930-9e45-2e2d7dd138ff
DOI: 10.21203/rs.3.rs-1919053/v1

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