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Article

Trials, Tribulations, and Trends in Tumor Modeling in Mice

1 Jan 2004

Abstract excerpt

Selection of mouse models of cancer is often based simply on availability of a mouse strain and a known compatible tumor. Frequently this results in use of tumor models long on history but short on homology and quality control. Other factors including genetics, sex, immunological status, method and site of tumor implantation, technical competence, biological activity of the tumor, protocol sequence and timing,...

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PMID: 15209404
DOI: 10.1080/01926230490424770

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