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Article

The relationship between open angle glaucoma, optic disc morphology and Alzheimer’s Disease: a Mendelian randomization study

2020-09-02

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD) and open angle glaucoma (OAG) are common age-related neurodegenerative disorders with shared pathological features, leading to the hypothesis that glaucoma may represent a type of “ocular Alzheimer’s disease”. However, no causal relationship has yet been established. <h4>Methods</h4> To test for a causal relationship, bi-directional two-sample Mendelian randomization an...

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Literature Corpus work
bfa75d18-95fc-5adb-b01c-be17de4310bc
DOI
10.1101/2020.08.30.20184846
Open publication

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The relationship between open angle glaucoma, optic disc morphology and Alzheimer’s Disease: a Mendelian randomization studyDOI 10.1101/2020.08.30.20184846
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