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Article

Genetic variation reveals the influence of steroid hormones on the risk of retinal neurodegenerative diseases.

Frontiers in endocrinology - 1 Jan 2022

Liu Kangcheng, Fan Huimin, Hu Hanying, Cheng Yanhua, Liu Jingying, You Zhipeng

Abstract excerpt

It is difficult to get evidence from randomized trials of a causal relationship between steroid hormones produced by the adrenal gland and gonad and retinal neurodegenerative disorders (RND). In this study, genetic variations of aldosterone (Aldo), androstenedione (A4), progesterone (P4), hydroxyprogesterone (17-OHP), and testosterone/17β-estradiol (T/E2) were obtained from genome-wide association studies as...

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Identifiers

PMID: 36704044
DOI: 10.3389/fendo.2022.1088557
PMCID: PMC9871487

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