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Article

The Associations Between Cataracts and Alzheimer's Disease: A Bidirectional Two-Sample Mendelian Randomization Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2023

Man Shulei, Chen Boran, Zhang Yifan, Xu Hanyue, Liu Yu, Gao Yuzhu, Chen Yi, Chen Qing, Zhang Ming

Abstract excerpt

BACKGROUND: The relationship between cataracts and Alzheimer's disease (AD) has been reported in recent observational studies. However, it is still unclear whether a causal effect of cataracts on AD or reverse causation exists. OBJECTIVE: To explore the association between cataracts and AD genetically, we performed a bidirectional two-sample Mendelian randomization study. METHODS: We obtained genetic instrumental...

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Identifiers

PMID: 36911941
DOI: 10.3233/JAD-221137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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